Title :
On the numerical analysis of coronary artery wall shear stress
Author :
Wolters, BJBM ; Slager, Cj ; Gijsen, FJH ; Wentze, JJ ; Krams, R. ; van de Vossel, F.N.
Author_Institution :
Dept. of Biomed. Eng., Eindhoven Univ. of Technol., Netherlands
Abstract :
A numerical analysis is performed in order to study coronary artery wall shear stress (WSS) and its dependence on (i) unsteadiness of the flow, (ii) motion and deformation of the blood vessel geometry and (iii) the shear thinning properties of blood. A non-stationary geometric model of the right coronary artery is developed from intravascular ultrasound measurements complemented with the 3D reconstructed measurement location and orientation. The velocity distribution in the model is computed by solving the arbitrary Lagrangian-Eulerian (ALE) formulation of the Navier-Stokes equations using a finite-element method. The averaged WSS pattern corresponding to time-dependent shear thinning flow in the non-stationary model is compared to the pattern corresponding to steady mean Newtonian flow in the rigid end-diastolic model
Keywords :
Navier-Stokes equations; biomechanics; biomedical ultrasonics; blood flow measurement; blood vessels; finite element analysis; geometry; shear deformation; stress measurement; 3D reconstructed measurement location; 3D reconstructed measurement orientation; Navier-Stokes equations; arbitrary Lagrangian-Eulerian formulation; blood shear-thinning properties; blood vessel deformation; blood vessel geometry; blood vessel motion; coronary artery wall shear stress; finite element method; flow unsteadiness; intravascular ultrasound measurements; nonstationary geometric model; numerical analysis; rigid end-diastolic model; steady mean Newtonian flow; time-dependent shear-thinning flow; velocity distribution; Arteries; Blood vessels; Distributed computing; Geometry; Motion analysis; Numerical analysis; Solid modeling; Stress; Ultrasonic imaging; Ultrasonic variables measurement;
Conference_Titel :
Computers in Cardiology 2001
Conference_Location :
Rotterdam
Print_ISBN :
0-7803-7266-2
DOI :
10.1109/CIC.2001.977618
