Regional and frequency dependencies of force development in myocardium: a simulation study

Author

Seemann, G. ; Sachse, FB ; Riedel, C. ; Werner, CD ; Dössel, O.

Author_Institution

Inst. fur Biomedizinische Technik, Karlsruhe Univ., Germany

fYear

2001

fDate

2001

Firstpage

345

Lastpage

348

Abstract

Heart models are used to simulate the electromechanical behavior of the myocardium. The simulations improve the comprehension of both physiology and pathologies. A model of an anisotropic and inhomogeneous myocardial area is introduced, in which simulations of electrical excitation and force development are performed. The model is based on a modified Noble-Varghese-Kohl-Noble (1998) model of electrophysiology, the bidomain model for excitation propagation and the force model of Rice, Winslow and Hunter (1999). Simulations with this myocardial model show the dependencies of the force development on frequency and on regional differences in the heart wall

Keywords

bioelectric phenomena; biomechanics; diseases; electrocardiography; electromechanical effects; electromyography; force; physiological models; simulation; Noble-Parghese-Kohl-Noble model; anisotropic inhomogeneous myocardial area; bidomain model; electrical excitation; electrophysiology; excitation propagation; force model; frequency dependency; heart models; heart wall regional differences; myocardial force development; myocardium electromechanical behavior; pathologies; physiology; regional dependency; simulation; Anisotropic magnetoresistance; Biomembranes; Conductivity; Extracellular; Frequency; Heart; Myocardium; Pathology; Poisson equations; Voltage;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology 2001

Conference_Location

Rotterdam

ISSN

0276-6547

Print_ISBN

0-7803-7266-2

Type

conf

DOI

10.1109/CIC.2001.977663

Filename

977663