High sensitivity biosensing using nano-slot nanolaser

We have developed photonic crystal nanolaser and applied it to sensing liquids and bio-molecules. In this study, a nano-slot structure is introduced into the nanolaser, which strengthens the mode localization and improves the sensitivity, stability, and resolution as a sensor. As a result, a very low detection limit of 5.1 pg/ml has been achieved for BSA protein. It will be applicable to high-throughput label-free biosensing, while a mechanism of such low detection limit with the nano-slot is of great interest to investigate.