Title :
Deriving DNA cryptographic keys based on evolutionary models
Author :
Hodorogea, Tatiana ; Otto, Ionas Szilard ; Janetta, Sarbu
Author_Institution :
Biozentrum Dept., Univ. of Basel, Basel, Switzerland
Abstract :
Based on the Central Dogma of Molecular Biology (CDMB), where we derive DNA Cryptographic Keys based on evolutionary models as public-key algorithms are based on mathematical functions rather than on substitution and permutation involving the use of two separate keys, in contrast to symmetric encryption, which uses only one key. When aligning the DNA sequences of the same gene from related species, there will usually be differences between the sequences because of evolution and because of the degeneracy of the genetic. Based on evolutionary models we extract and align the DNA sequences of the same gene from related chosen species with respect to human DNA Sequences. The alignment in the evolutionary system pipeline is realized with ProbCons tool, which is a pair-hidden Markov model-based on progressive alignment algorithm that primarily differs from most typical approaches in its use of maximum expected accuracy. After aligning our extracted DNA Sequences with ProbCons we derive the private/public pair DNA cryptographic keys based on evolutionary models mathematical functions.
Keywords :
DNA; Markov processes; public key cryptography; DNA cryptographic keys; DNA sequences; Markov model; ProbCons tool; evolutionary model; evolutionary system pipeline; mathematical function; molecular biology; permutation; progressive alignment algorithm; public key algorithm; symmetric encryption; Bioinformatics; Cryptography; DNA; Genomics; Hidden Markov models; Java; DNA cryptographic keys; Hidden Markov Model; Public-key Introduction; evolutionary models;
Conference_Titel :
Carpathian Control Conference (ICCC), 2011 12th International
Conference_Location :
Velke Karlovice
Print_ISBN :
978-1-61284-360-5
DOI :
10.1109/CarpathianCC.2011.5945835