Dermal wound healing-remodeling phase: A biological review

Author

Azizi, Aydin ; Osgouie, Kambiz Ghaemi

Author_Institution

Dept. of Mech. Eng., Sharif Univ. of Technol., Tehran, Iran

Volume

2

fYear

2010

fDate

26-28 Feb. 2010

Firstpage

88

Lastpage

90

Abstract

Though wound healing process is well-researched, this area is poorly known. One reason is that all interactions have not been discovered, the main reason, though, is that the involved processes interact in a very complicated manner with nonlinear feedback. Such complex feedback mechanisms can be easily addressed by mathematical modeling. This paper contains a review of the mathematical modeling of cell interaction with extracellular matrix components during the process of dermal wound healing with focusing on remodeling phase. The models are of partial differential equation type and solved by finite element method.

Keywords

cellular biophysics; feedback; finite element analysis; partial differential equations; skin; wounds; cell interaction; complex feedback mechanisms; dermal wound healing remodeling phase; extracellular matrix components; finite element method; mathematical modeling; nonlinear feedback; partial differential equation; Dermis; Electrochemical machining; Extracellular; Feedback; Fibroblasts; Finite element methods; Injuries; Mathematical model; Skin; Wounds; finite element; mathematical model; remodeling phase; wound healing;

fLanguage

English

Publisher

ieee

Conference_Titel

Computer and Automation Engineering (ICCAE), 2010 The 2nd International Conference on

Conference_Location

Singapore

Print_ISBN

978-1-4244-5585-0

Electronic_ISBN

978-1-4244-5586-7

Type

conf

DOI

10.1109/ICCAE.2010.5451392

Filename

5451392