Chromatin texture characterization using multiscale fractal dimension

A new approach to chromatin texture characterization is proposed, based on the recently introduced concept of multiscale fractal dimension. Promising results for differentiating normal from abnormal blood cells have been obtained by considering the peaks of multiscale fractal dimension after Minkowski-Bouligand dilation of the nucleus gray tones. Results for a lymphocyte database exemplify the potential of the method with respect to nuclear texture discrimination. A brief review of related works is also included, focusing on statistical approaches.