DocumentCode :
2164456
Title :
Study on ultrastructural changes of anterior pituitary in rats exposed to PEMW
Author :
XiaoMing, Su ; Guozhen, Guo ; Xiaowei, Liu ; Jiaxing, Zhou ; Yuhong, Qi ; Xiaowu, Wang ; Lihua, Zeng ; Kangchu, Li ; Yongbin, Chen
Author_Institution :
Dept. of Radiat. Med., Med. Univ., Xi´´an
fYear :
2008
fDate :
2-5 Nov. 2008
Firstpage :
1048
Lastpage :
1051
Abstract :
The document is to observe the changes of ultrastructure of endocrine cell in anterior pituitary after being exposed to PEMW to explore the possible injury characteristics. 28 male Sparague-Dawley rats were divided into 4 groups (7 rats in each group), the control group was put in the boxes without irradiation. At 24 h after exposure to PEMW (E=100 kVmiddotm-1, 10000, 100000, 300000 pulses), the transmission electron microscope was used to observe the ultrastructural changes of anterior pituitary. The result showed that ultrastructures of anterior pituitary were obviously changed in irradiated groups at 10000 pulses, especially in prolactin cells and growth hormone cells, including evacuation of secretory granule, the mitochondrial vacuolization and distinct dilatation of endoplasmic reticulum. The injury gradually aggravate followed by pulses increase. The changes at 300000 pulses were the most severe. In conclusion, PEMW can lead injury to endocrine cells of anterior pituitary in rats, mitochondria and rough endoplasmic reticulum are the main injured organelles.
Keywords :
cellular effects of radiation; Sparague-Dawley rats; anterior pituitary; endocrine cell; endoplasmic reticulum; growth hormone cells; prolactin cells; rough endoplasmic reticulum; transmission electron microscope; ultrastructural changes; Animals; EMP radiation effects; Electromagnetic radiation; Electromagnetic scattering; Electron microscopy; Endocrine system; Injuries; Lenses; Rats; Shape control;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Antennas, Propagation and EM Theory, 2008. ISAPE 2008. 8th International Symposium on
Conference_Location :
Kunming
Print_ISBN :
978-1-4244-2192-3
Electronic_ISBN :
978-1-4244-2193-0
Type :
conf
DOI :
10.1109/ISAPE.2008.4735402
Filename :
4735402
Link To Document :
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