Towards the simultaneous on-line estimation of the compliance and outflow resistance of the cerebrospinal fluid system

Accurate estimates of the compliance and outflow resistance of the human cerebrospinal fluid system are important for diagnosis of a medical condition known as hydrocephalus. In this paper we design an observer which provides simultaneous on-line estimates of the outflow resistance and compliance, to our knowledge the first method to do so. It´s performance is experimentally verified using the same apparatus used to perform actual patient diagnoses and a specially designed physical model of the human cerebrospinal fluid system.