DocumentCode :
2175421
Title :
Developing the High-Localized Single-Particle/Single-Cell Assay for Low Doses Irradiation In Vitro
Author :
Hu, Zhi-Wen ; Chen, Lian-Yun
Author_Institution :
Coll. of Phys. & Electron. Inf. Eng., Wenzhou Univ., Wenzhou, China
fYear :
2009
fDate :
17-19 Oct. 2009
Firstpage :
1
Lastpage :
4
Abstract :
Single-Particle Microbeam (SPM) is uniquely capable of precisely delivering a predefined number of charged particles (precise doses of radiation) to individual cells or sub-cellular targets in situ. Here, we scrutinize and formulate the application of calibration and cell registration, image stitching, standard irradiation protocols, and give a critical review of the related pivotal evolution during developing the high-localized single-particle/singlecell assay for low doses irradiation in vitro at the CAS-LIBB SPM at the Key Laboratory of Ion beam Bioengineering, Chinese Academy of Sciences (CAS-LIBB).
Keywords :
biological effects of ionising radiation; calibration; cellular effects of radiation; dosimetry; CAS-LIBB SPM; Chinese Academy of Sciences; Key Laboratory of Ion beam Bioengineering; calibration; cell registration; high-localized single-particle; image stitching; low dose irradiation in vitro; single cell assay; single-particle microbeam; standard irradiation protocol; Biomedical engineering; Calibration; Focusing; Image recognition; In vitro; Ion beams; Ionizing radiation; Laboratories; Physics; Scanning probe microscopy;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Biomedical Engineering and Informatics, 2009. BMEI '09. 2nd International Conference on
Conference_Location :
Tianjin
Print_ISBN :
978-1-4244-4132-7
Electronic_ISBN :
978-1-4244-4134-1
Type :
conf
DOI :
10.1109/BMEI.2009.5304835
Filename :
5304835
Link To Document :
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