Title :
The Model Experiments on a Novel Drug Delivery Device
Author :
Chen, Yang-Zhi ; Wei, Jin-Song ; Xiao, Jian
Author_Institution :
Sch. of Mech. & Automobile Eng., South China Univ. of Technol., Guangzhou, China
Abstract :
The model of a novel drug delivery device of gastrointestinal microcapsule in a gas pressure driving way is proposed. The model experiments have been carried out to investigate into the main factors impacting on the performance of capsule, such as ultrasonic frequency, the relationship between the quantity and reaction time of the selected reactants, the relationship between the carried drug capacity and releasing drug time; and the optimal parameters of the capsule model are recommended on the basis of experimental results. Finally, the capsule structure of the model is proved being safe through strength analysis by ANSYS.
Keywords :
biomedical materials; drug delivery systems; finite element analysis; ANSYS; drug carrying capacity; drug delivery device; drug release time; gastrointestinal microcapsule; reactant quantity; reactant reaction time; ultrasonic frequency; Automotive engineering; Chemicals; Drug delivery; Frequency; Gastrointestinal tract; Materials testing; Pharmaceutical technology; Pressure control; Temperature; Ultrasonic imaging;
Conference_Titel :
Biomedical Engineering and Informatics, 2009. BMEI '09. 2nd International Conference on
Conference_Location :
Tianjin
Print_ISBN :
978-1-4244-4132-7
Electronic_ISBN :
978-1-4244-4134-1
DOI :
10.1109/BMEI.2009.5304935
