MRI: advances in the structural, molecular identification, and characterization of atherosclerotic plaques

Non-invasive, high-resolution magnetic resonance has the potential to image atherosclerotic plaque and to determine its composition and micro-anatomy. We summarize the rationale for plaque imaging, and describe the characteristics of plaque using existing MRI techniques. The use of MRI in human disease and in animal models, particularly rabbits and mice, is presented. Current and future applications of MRI, including new contrast agents and molecular imaging are also discussed.