Narrow Beam SPR Biosensor and Experimental Study

Author

Yan, Shuo ; Fang, Yiqun ; Yu, Xinglong

Author_Institution

Naval Med. Res. Inst., Shanghai, China

fYear

2009

fDate

17-19 Oct. 2009

Firstpage

1

Lastpage

5

Abstract

Surface plasmon resonance (SPR) biosensor can be used to analyze bio-specific interaction and offer parameters like dynamic characteristics and concentration of the biomolecular interaction by detecting the refractive index change of the sample. This paper presents an experimental equipment of SPR biosensor with narrow incident beam, which can avoid random light intensity distribution. The experiment results indicate that SPR sensing with narrow incident beam can monitor the refractive index change of the samples and possess a primary sensitivity of 0.001 RIU.

Keywords

biological techniques; molecular biophysics; optical sensors; refractive index; surface plasmon resonance; bio-specific interaction; biomolecular interaction; biosensor; dynamic characteristics; narrow incident beam; random light intensity distribution; refractive index; surface plasmon resonance; Biomedical optical imaging; Biosensors; Charge coupled devices; Mirrors; Optical films; Optical refraction; Optical sensors; Optical variables control; Refractive index; Resonance;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Engineering and Informatics, 2009. BMEI '09. 2nd International Conference on

Conference_Location

Tianjin

Print_ISBN

978-1-4244-4132-7

Electronic_ISBN

978-1-4244-4134-1

Type

conf

DOI

10.1109/BMEI.2009.5305175

Filename

5305175