DocumentCode
2186490
Title
A novel approach to quantitative analysis of electrophoretic gel images of DNA fragments
Author
Bajla, I. ; Holländer, I. ; Burg, K. ; Fluch, S.
Author_Institution
Unit of High Performance Image Process., ARC Seibersdorf Research GmbH, Austria
fYear
2002
fDate
2002
Firstpage
899
Lastpage
902
Abstract
A novel methodology of DNA gel image analysis has been proposed that is based on 2D image processing methods instead of previously used 1D Gaussian deconvolution. The algorithms specifically tailored to band boundary detection and image intensity homogeneity characterization have been developed. The proposed methodology involves a modified type of user interaction.
Keywords
DNA; biological techniques; deconvolution; edge detection; electrophoresis; gels; image processing; molecular biophysics; 1D Gaussian deconvolution; 2D image processing methods; DNA fragments; DNA molecules separation; biophysical research technique; digitized electrophoretic gels; electrophoretic gel images; image intensity homogeneity characterization; user interaction; Biotechnology; Convolution; DNA; Deconvolution; Electrokinetics; Image analysis; Image processing; Information analysis; Integral equations; Software systems;
fLanguage
English
Publisher
ieee
Conference_Titel
Biomedical Imaging, 2002. Proceedings. 2002 IEEE International Symposium on
Print_ISBN
0-7803-7584-X
Type
conf
DOI
10.1109/ISBI.2002.1029406
Filename
1029406
Link To Document