DocumentCode :
2187495
Title :
Haemodynamic Effect of Coronary Angulations on Subsequent Development of Coronary Artery Disease: A Preliminary Study
Author :
Chaichana, Thanapong ; Sun, Zhonghua ; Jewkes, James
Author_Institution :
Dept. of Imaging & Appl. Phys., Curtin Univ., Perth, WA, Australia
fYear :
2010
fDate :
7-10 Dec. 2010
Firstpage :
39
Lastpage :
43
Abstract :
The aim of this study is to investigate the hemodynamic effect of the angulations in the left coronary bifurcation on subsequent development of coronary artery disease. Eight 3D left coronary artery models were generated based on the anatomical details and simulated for numerical analysis. The angulations at the left coronary bifurcation were simulated with angles ranging from 120°, 105°, 90°, 75°, 60°, 45°, 30° to 15°. Computational fluid dynamic models were produced for analysis of flow velocity, wall pressure and wall shear stress. Our results showed that wide angled models produced low wall shear stress and high wall pressure at the left coronary bifurcation regions, whereas, flow pattern was more smooth and laminar with narrow angled models than those with wide angle models. Our analysis indicates the flow-field correlation between coronary angulation and development of atherosclerosis. Future studies are required to analyse the realistic coronary models from patients´ data with different degree of coronary stenosis.
Keywords :
biology computing; cardiology; computational fluid dynamics; diseases; laminar flow; mesh generation; patient diagnosis; solid modelling; 3D models; atherosclerosis; computational fluid dynamic; coronary angulation; coronary artery; coronary bifurcation; coronary stenosis; disease; flow field correlation; flow pattern; flow velocity; laminar flow; wall pressure; wall shear stress; Arteries; Computational fluid dynamics; Computational modeling; Diseases; Hemodynamics; Solid modeling; Stress; Angulation; Blood flow; Coronary artery disease; Flow velocity; Plaque; Simulation;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
e-Science Workshops, 2010 Sixth IEEE International Conference on
Conference_Location :
Brisbane, QLD
Print_ISBN :
978-1-4244-8988-6
Electronic_ISBN :
978-0-7695-4295-9
Type :
conf
DOI :
10.1109/eScienceW.2010.16
Filename :
5693139
Link To Document :
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