Dynamic Contrast Enhanced Imaging of Mice Kidney Metabolism Using High-Temperature Superconducting RF Coil on a 3T MRI System

Dynamic contrast enhanced (DCE) MRI is a potential technique to monitor the temporal evolution of signal change for the specific tissue microcirculation or tumor angiogenesis. In this study, we implemented high-temperature superconducting (HTS) RF coil system on DCE application of in-vivo mice kidney metabolism. Compared to a conventional copper coil, the improvement of the signal-to-noise ratio (SNR) of approximately 2.7 folds and average signal change (DeltaS) of 4 folds was shown in the preliminary results. The capability of HTS coil on DCE MRI was demonstrated and further investigation of tumor cancer model is expected.