Title :
Dynamic Contrast Enhanced Imaging of Mice Kidney Metabolism Using High-Temperature Superconducting RF Coil on a 3T MRI System
Author :
Chen, Kai-Yuan ; Kuo, Li-Wei ; Lin, Wei-Ting ; Su, Chia-Hao ; Chen, Jyh-Homg
Author_Institution :
Nat. Taiwan Univ., Taipei
Abstract :
Dynamic contrast enhanced (DCE) MRI is a potential technique to monitor the temporal evolution of signal change for the specific tissue microcirculation or tumor angiogenesis. In this study, we implemented high-temperature superconducting (HTS) RF coil system on DCE application of in-vivo mice kidney metabolism. Compared to a conventional copper coil, the improvement of the signal-to-noise ratio (SNR) of approximately 2.7 folds and average signal change (DeltaS) of 4 folds was shown in the preliminary results. The capability of HTS coil on DCE MRI was demonstrated and further investigation of tumor cancer model is expected.
Keywords :
biomedical MRI; cancer; kidney; superconducting coils; tumours; 3T MRI system; dynamic contrast enhanced imaging; high-temperature superconducting RF coil; kidney metabolism; signal-to-noise ratio; tissue microcirculation; tumor angiogenesis; tumor cancer model; Biochemistry; Copper; High temperature superconductors; Magnetic resonance imaging; Mice; Monitoring; Neoplasms; Radio frequency; Signal to noise ratio; Superconducting coils;
Conference_Titel :
Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging, 2007. NFSI-ICFBI 2007. Joint Meeting of the 6th International Symposium on
Conference_Location :
Hangzhou
Print_ISBN :
978-1-4244-0949-5
Electronic_ISBN :
978-1-4244-0949-5
DOI :
10.1109/NFSI-ICFBI.2007.4387744
