Comparative study of ECAT HRRT and microPET® R4 for animal PET studies

Author

Knoess, Christof ; Lenox, Mark ; Goble, Rhonda N. ; Siegel, Stefan ; Smith, Anne M. ; Vollmar, Stefan ; Winkeler, Alexandra ; Jacobs, Andreas ; Fluegge, Guenter ; Wienhard, Klaus ; Heiss, Wolf-Dieter

Author_Institution

Max-Planck-Inst. for Neurological Res., Cologne, Germany

Volume

2

fYear

2002

fDate

10-16 Nov. 2002

Firstpage

807

Abstract

In vivo studies on animals are required for the development of new drugs and radioactive tracers, the monitoring of gene therapy and the development of new medical treatments. Two high resolution positron emission tomographs (PET) were compared in the scope of this work with regard to their suitability for high resolution animal PET scans. The ECAT HRRT is a dedicated whole human brain scanner with a resolution of less than 2.5 mm in the center of the field of view (FOV). With its extended FOV the HRRT is also suitable for animal scans with more than one animal simultaneously. The microPET® R4 is a dedicated animal PET scanner, designed for studies of rodents.

Keywords

brain; positron emission tomography; ECAT HRRT; animal PET studies; high resolution positron emission tomographs; microPET R4; rodents; whole human brain scanner; Animals; Biomedical monitoring; Drugs; Gene therapy; Humans; In vivo; Medical treatment; Positron emission tomography; Radioactive decay; Rodents;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2002 IEEE

Print_ISBN

0-7803-7636-6

Type

conf

DOI

10.1109/NSSMIC.2002.1239448

Filename

1239448