Influence of low-frequency rTMS on EEG of epileptic rats

Author

Guanghao, Zhang ; Linxia, Li ; Huo Xiaolin ; Tao, Song

Author_Institution

Chinese Acad. of Sci., Beijing

fYear

2007

fDate

12-14 Oct. 2007

Firstpage

338

Lastpage

340

Abstract

The present research was to study the influence of low-frequency rTMS on epilepsy by EEG analysis. A train of 100, 0.5 Hz rTMS was applied on 15 Sprague-Dawley rats, and sham stimulation was also applied. EEG was recorded before stimulation and within 1 minute after rTMS and sham stimulation. Results showed that mean absolute power (MAP) of gamma band and relative power (RP) of beta and gamma band decreased significantly after low-frequency rTMS. In another experiment, pentylenetetrazol was injected immediately after 100 impulses of 0.5 Hz rTMS. Results showed that seizure susceptibility decreased greatly. These results indicate that low-frequency rTMS has certain suppressive effects on epilepsy due to power spectrum reduction.

Keywords

biomagnetism; diseases; electroencephalography; EEG; Sprague-Dawley rats; electroencephalography; epileptic rats; frequency 0.5 Hz; low frequency rTMS; mean absolute power; power spectrum; repetitive transcranial magnetic stimulation; Bones; Cerebral cortex; Coils; Electroencephalography; Epilepsy; Frequency; Magnetic fields; Magnetic stimulation; Psychology; Rats;

fLanguage

English

Publisher

ieee

Conference_Titel

Noninvasive Functional Source Imaging of the Brain and Heart and the International Conference on Functional Biomedical Imaging, 2007. NFSI-ICFBI 2007. Joint Meeting of the 6th International Symposium on

Conference_Location

Hangzhou

Print_ISBN

978-1-4244-0949-5

Electronic_ISBN

978-1-4244-0949-5

Type

conf

DOI

10.1109/NFSI-ICFBI.2007.4387769

Filename

4387769