Impact of respiratory motion on the detection of solitary pulmonary nodules with SPECT tumor imaging of NeoTect

Author

Smyczynski, M.S. ; Gifford, H.C. ; Farncombe, T.H. ; Segars, W.P. ; Tsui, B.M.W. ; King, M.A.

Author_Institution

Div. of Nucl. Medicine, Massachusetts Univ. Med. Center, Worcester, MA, USA

Volume

2

fYear

2002

fDate

10-16 Nov. 2002

Firstpage

838

Abstract

We have previously modeled the respiratory motion of solitary pulmonary nodules (SPN) based on the change of location of anatomic structures within the lungs identified on breath-held CT images of volunteers acquired at two different stages of respiration. The goal of this investigation is to make use of this modeling to investigate the impact of respiratory motion on the detection of solitary pulmonary nodules with single photon emission computed tomographic (SPECT) imaging using Tc-99m labeled NeoTect. To do this, end-expiration and respiration-averaged source and attenuation maps were created from the NCAT phantom and input to the SIMIND Monte Carlo package.

Keywords

Monte Carlo methods; lung; medical image processing; single photon emission computed tomography; tumours; NCAT phantom; NeoTect; SIMIND Monte Carlo package; SPECT tumor imaging; Tc; Tc-99m; lungs; respiratory motion; single photon emission computed tomography; solitary pulmonary nodules; Attenuation; Computed tomography; Imaging phantoms; Lungs; Monte Carlo methods; Motion detection; Neoplasms; Optical computing; Packaging; Single photon emission computed tomography;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2002 IEEE

Print_ISBN

0-7803-7636-6

Type

conf

DOI

10.1109/NSSMIC.2002.1239455

Filename

1239455