DocumentCode :
2196590
Title :
A Model of Intelligent Controller for Hypothyroidism Treatment
Author :
Martins, Luiz G A ; Monteiro, Luiz H A
Author_Institution :
Univ. Fed. de Uberlandia, Uberlandia, Brazil
fYear :
2010
fDate :
June 29 2010-July 1 2010
Firstpage :
472
Lastpage :
479
Abstract :
Hypothyroidism results from an insufficiency either in the production or/and in the action of the thyroid hormones. Most of the patients in hypothyroidism state must adopt hormonal replacement therapy for all their lives. An intelligent controller model for supplying therapeutic drugs to primary hypothyroidism patients, without the thyroid gland, is investigated in this work. Two multilayer perceptron neural networks are used to predict the concentrations of the hormones TSH and T4 in the blood. The controller, based on a set of production rules, uses these forecasts and the current concentrations of such hormones for calculating the necessary drug dosage to be released. Beyond the controller maintaining such concentrations inside regularity bands, it is also able of preventing abrupt changes on the time evolution of these concentrations.
Keywords :
intelligent control; multilayer perceptrons; patient treatment; T4; TSH; hormonal replacement therapy; hypothyroidism patients; hypothyroidism treatment; intelligent controller; multilayer perceptron neural networks; therapeutic drugs; thyroid gland; thyroid hormones; Artificial neural networks; Biochemistry; Drugs; Glands; Maintenance engineering; Mathematical model; Production; Intelligent control; neural networks; production rules; thyroid hormones;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Computer and Information Technology (CIT), 2010 IEEE 10th International Conference on
Conference_Location :
Bradford
Print_ISBN :
978-1-4244-7547-6
Type :
conf
DOI :
10.1109/CIT.2010.106
Filename :
5578145
Link To Document :
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