Dynamic display and quantitative analysis of three-dimensional left ventricular pathology

Techniques have been developed for automated extraction and dynamic interactive display of three-dimensional (3-D) left-ventricular (LV) surface anatomy from cine computer tomography (CT) images using a PC-based image-display architecture. Images of both endocardial and myocardial surface anatomy are generated from multiple views at multiple time instances to demonstrate various LV pathologies, including apical akinesis, apical and posterior aneurysms, LV failure, IHSS, and a left atrial myxoma. Surface generation requires interpolation between scans, surface tracking, and rendering. Generation of 60 views corresponding to a single time instance requires approximately 15 minutes. LV dimensions are measured between two or more surface points using one or more views. Dynamic interactive display and measurement of surface anatomy provides a valuable tool for improved understanding and quantitative analysis of LV shape, size, and dimensions in the presence of these pathologies