• DocumentCode
    2207593
  • Title

    Development of a chemically crosslinked poly(vinyl alcohol) hydrogel for injectable nucleus pulposus replacement

  • Author

    Binetti, V.R. ; Marcolongo, M. ; Lowman, A.M.

  • Author_Institution
    Mater. Sci. & Eng., Drexel Univ., Philadelphia, PA, USA
  • fYear
    2012
  • fDate
    16-18 March 2012
  • Firstpage
    378
  • Lastpage
    379
  • Abstract
    Poly(vinyl alcohol) (PVA) hydrogels have been chemically crosslinked using poly(ethylene glycol) diglycidyl ether (PEG-DGE) to develop a material for injectable nucleus pulposus replacement. The effects of PVA and PEG-DGE concentrations on compressive modulus and swelling have been deteremined in addition to the cytotoxic effects of crosslinking PVA with PEG-DGE.
  • Keywords
    biomechanics; biomedical materials; hydrogels; internal stresses; swelling; chemically crosslinked poly(vinyl alcohol) hydrogel; compressive modulus; cytotoxic effects; injectable nucleus pulposus replacement; poly(ethylene glycol) diglycidyl ether; Barium; Biomedical engineering; Educational institutions; Implants; Materials; Strain; Testing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference (NEBEC), 2012 38th Annual Northeast
  • Conference_Location
    Philadelphia, PA
  • ISSN
    2160-7001
  • Print_ISBN
    978-1-4673-1141-0
  • Type

    conf

  • DOI
    10.1109/NEBC.2012.6207122
  • Filename
    6207122