Can neural circuit structure define its signal patterns?

Author

Wolpert, S.

Author_Institution

Sch. of Sci., Eng. & Technol., Pennsylvania State Univ., Harrisburg, PA

fYear

1997

fDate

21-22 May 1997

Firstpage

13

Lastpage

14

Abstract

In this study, a comprehensive neuronal model of a living central pattern generator network was implemented in custom analog VLSI hardware. After the model was designed and assembled, signals denoting membrane potential in each cell were seen to compare faithfully and regularly with those in their living counterparts, but as key cell parameters were varied, the network was observed to settle into alternate signal patterns and rhythms. This suggests that defining the structure of a nerve network is not enough to specify the signals that will reside therein

Keywords

VLSI; analogue processing circuits; aquaculture; bioelectric potentials; biological techniques; biomembrane transport; living systems; neural chips; neurophysiology; physiological models; VLSI neuromime; cell parameters; custom analog VLSI hardware; living central pattern generator network; medicinal leech; membrane potential; model; nerve network structure; neuronal model; rhythms; signal patterns; Assembly; Biological system modeling; Biomembranes; Cells (biology); Circuits; Mathematical model; Rhythm; Steady-state; Testing; Very large scale integration;

fLanguage

English

Publisher

ieee

Conference_Titel

Bioengineering Conference, 1997., Proceedings of the IEEE 1997 23rd Northeast

Conference_Location

Durham, NH

Print_ISBN

0-7803-3848-0

Type

conf

DOI

10.1109/NEBC.1997.594935

Filename

594935