DocumentCode
2213382
Title
Distances in hominidae family MTDNA from nucleotide genomic signals
Author
Cristea, Paul Dan ; Tuduce, Rodica
Author_Institution
Biomed. Eng. Center, Univ. Politeh. pf Bucharest, Bucharest, Romania
fYear
2012
fDate
11-13 April 2012
Firstpage
526
Lastpage
529
Abstract
The nucleotide genomic signal (NuGS) methodology allows computing the distance between various species in a family, or between individuals in the same species, starting from on the distance between homologous genes, or between conserved equivalent non-coding genomic regions. NuGSs, specifically nucleotide imbalance (N) and nucleotide pair imbalance (P) signals for the mitochondrial DNA (mtDNA), are used to evaluate at molecular level the distances among six extant and one fossil species of the Hominidae family. The areas encoding the 37 mitochondrial genes are well conserved for species in the same family, so that the distances between mtDNA genes are small. A surprising feature is the regularity of the variation of gene distance along the mtDNA sequence.
Keywords
DNA; genomics; molecular biophysics; conserved equivalent noncoding genomic region; fossil species; gene distance variation; hominidae family; homologous gene; mitochondrial DNA; mtDNA sequence; nucleotide genomic signal methodology; nucleotide imbalance signal; nucleotide pair imbalance signal; Abstracts; Bioinformatics; DNA; Genomics; Hominidae; Mitochondrial DNA; Nucleotide Genomic Signals; Signal representation;
fLanguage
English
Publisher
ieee
Conference_Titel
Systems, Signals and Image Processing (IWSSIP), 2012 19th International Conference on
Conference_Location
Vienna
ISSN
2157-8672
Print_ISBN
978-1-4577-2191-5
Type
conf
Filename
6208194
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