Title :
The galaxy method for the 3-D spatial registration of PET images to Talairach brain atlas
Author :
Levy, A.V. ; Alexoff, D. ; Hode, F. ; Denis, M. ; Bertollo, D. ; Dhawan, A.P. ; Logan, J. ; Andrews, B. ; Volkow, N.D.
Author_Institution :
Dept. of Chem., Brookhaven Nat. Lab., Upton, NY, USA
fDate :
31 Oct-3 Nov 1996
Abstract :
Human brain function is studied by averaging many PET images in order to enhance the signal to noise ratio of weak group-specific patterns caused by medication, illness, or functional activation. Present registration methods by Woods and Friston (SPM), compute 3 translations and 3 rotations to register each PET image to a reference anatomical atlas using a 6 degree of freedom optimization method. By using only a 2 degree of freedom optimization method, the present method decreases the computing time down to 70 sec in a SUN Sparc2 CPU; this is a speed increment by a factor of 3 to 15 times over previous methods. Experimental results for 24 FDG-PET images also indicate that the present method improves the accuracy of the registration to a mean error of 0.48 mm and a maximum error of 2.47 mm
Keywords :
brain; image registration; medical image processing; positron emission tomography; 2 degree of freedom optimization method; 3-D spatial registration; 70 sec; Talairach brain atlas; clusters; computing time; galaxy method; human brain function; positron emission tomography images; reference anatomical atlas; registration accuracy; weak group-specific patterns; Biomedical imaging; Brain; Humans; Laboratories; Optimization methods; Pixel; Positron emission tomography; Registers; Shape; Signal to noise ratio;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.652006
