Title :
Functional monolayer surfaces on gold nanoparticles for specific binding of histidine-tagged proteins
Author :
Barton, Christopher S. ; Waniganayake, Lakshmi ; Wei, Gang ; McMurchie, Edward J. ; Leifert, Wayne R. ; Jamting, Asa ; Raguse, Burkhard ; Wieczorek, Lech
Author_Institution :
CSIRO Ind. Phys., Lindfield, NSW
Abstract :
Functionalised gold nanoparticles, capable of specifically binding histidine-tagged proteins, are of interest as their unique optical properties can facilitate the study of protein-protein interactions. Citrate-stabilized gold nanoparticles were functionalised with surface capping agents to specifically bind histidine-tagged proteins, and to test the stability of the nanoparticle solutions under various conditions.
Keywords :
gold; monolayers; nanoparticles; proteins; stability; citrate-stabilized; functional monolayer surfaces; gold nanoparticles; histidine-tagged proteins; protein-protein interactions; specific binding; stability; surface capping agents; surface modification; unique optical properties; Australia; Electromagnetic wave absorption; Gold; Nanoparticles; Optical sensors; Plasmons; Proteins; Spectroscopy; Stability; Testing;
Conference_Titel :
Nanoscience and Nanotechnology, 2006. ICONN '06. International Conference on
Conference_Location :
Brisbane, Qld.
Print_ISBN :
1-4244-0452-5
Electronic_ISBN :
1-4244-0452-5
DOI :
10.1109/ICONN.2006.340591
