• DocumentCode
    2228306
  • Title

    An equivalent Markov model for Gillespie´s Stochastic Simulation Algorithm for biochemical systems

  • Author

    Bustin, Ronit ; Messer, Hagit

  • Author_Institution
    Sch. of Electr. Eng., Tel-Aviv Univ., Tel-Aviv, Israel
  • fYear
    2006
  • fDate
    4-8 Sept. 2006
  • Firstpage
    1
  • Lastpage
    5
  • Abstract
    Mathematical/statistical modeling of biological systems is a desired goal for many years. It aims to be able to accurately predict the operation of such systems under various scenarios using computer simulations. In this paper we revisit Gillespie´s Stochastic Simulation Algorithm for biochemical systems and we suggest an equivalent Markov Model for it. We show that under certain conditions it is a 1st order homogenous Markov process and we analyze these conditions. Our suggested model can be used to simulate the probability density function of a biochemical processes which, in turn, can be used for applying statistical signal processing and information theory tools on them.
  • Keywords
    DNA; Markov processes; information theory; probability; signal processing; 1st order homogenous Markov process; Gillespie stochastic simulation; biochemical process; biochemical systems; biological systems; computer simulations; equivalent Markov model; information theory; mathematical modeling; probability density function; statistical modeling; statistical signal processing; Abstracts; Biological system modeling; Mathematical model; Radiation detectors; Tin; Vectors;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Signal Processing Conference, 2006 14th European
  • Conference_Location
    Florence
  • ISSN
    2219-5491
  • Type

    conf

  • Filename
    7071767