SH-SAW biosensor based on pH change

Author

Kondoh, Jun ; Matsui, Yusuke ; Shiokawa, Shigeki

Author_Institution

Fac. of Eng., Shizuoka Univ., Hamamatsu

fYear

1993

fDate

31 Oct-3 Nov 1993

Firstpage

337

Abstract

This paper describes an enzyme-immobilized biosensor using a surface acoustic wave (SAW) device fabricated on 36° rotated Y-cut, X-propagating LiTaO₃. The sensing wave on the substrate is a predominantly shear-horizontal-mode SAW (SH-SAW) and is affected by a strong acoustoelectric interaction between the electric field and electric properties of the materials in the adjacent liquid. As an example of an electric property, the pH change associated with an enzyme reaction leads to measurable perturbation in the wave-propagation characteristics. Taking advantage of this phenomenon, we realized a SAW biosensor which consists of an immobilized urease film on the surface. Also, highly sensitive detection for the urea solution was obtained in our preliminary experiments

Keywords

acoustoelectric transducers; biosensors; surface acoustic wave devices; ultrasonic devices; LiTaO₃; SH-SAW biosensor; Y-cut LiTaO₃; acoustoelectric interaction; enzyme-immobilized biosensor; pH change; shear-horizontal-mode SAW; urea solution; urease film; Acoustic sensors; Acoustic signal detection; Biochemistry; Biosensors; Chemical and biological sensors; Electric potential; Electromechanical sensors; Metallization; Permittivity; Surface acoustic waves;

fLanguage

English

Publisher

ieee

Conference_Titel

Ultrasonics Symposium, 1993. Proceedings., IEEE 1993

Conference_Location

Baltimore, MD

Print_ISBN

0-7803-2012-3

Type

conf

DOI

10.1109/ULTSYM.1993.339472

Filename

339472