Complete evaluation of conformational MW effects on ACh channels with parallel computing

Author

Tarricone, L.

Author_Institution

Istituto di Elettronica, Perugia Univ., Italy

Volume

2

fYear

1996

fDate

17-21 June 1996

Firstpage

1093

Abstract

The authors present here a parallel implementation and optimization of a Markov model simulating the acetylcholine-receptor (ACh) channel response to 2.45 GHz fields. It overcomes the limitations of a previous implementation, allowing a complete understanding of the simulated phenomenon. The main experimentally observed effects of microwaves on ACh channels are theoretically explained, and an energetical mapping of ACh conformational changes achieved.

Keywords

Markov processes; biological effects of microwaves; biology computing; biomembrane transport; biomolecular effects of radiation; cellular effects of radiation; neurophysiology; parallel processing; physiological models; proteins; 2.45 GHz; Markov model; acetylcholine-receptor channel response; cellular radiation biology; conformational microwave effects; energetical mapping; ionic protein channels; model optimization; molecular radiation biology; parallel computing; Biological system modeling; Biological systems; Biomembranes; Cells (biology); Computational modeling; Electromagnetic fields; Frequency; Parallel processing; Proteins; Stochastic processes;

fLanguage

English

Publisher

ieee

Conference_Titel

Microwave Symposium Digest, 1996., IEEE MTT-S International

Conference_Location

San Francisco, CA, USA

ISSN

0149-645X

Print_ISBN

0-7803-3246-6

Type

conf

DOI

10.1109/MWSYM.1996.511220

Filename

511220