Title :
Silicon photomultiplier: Detector for highly sensitive detection of fluorescence signals
Author :
Dhulla, Vinit ; Cheng, Lu ; Gudkov, Georgiy ; Tsupryk, Andriy ; Tovkach, Ivan ; Gorfinkel, Vera
Author_Institution :
Dept. of Electr. Eng., Stony Brook Univ., Stony Brook, NY
Abstract :
We demonstrate use of silicon photomultipliers (SiPMs) in single photon counting mode for detection of very weak laser induced fluorescence (LIF). Detection of LIF in DNA-sequencing has been performed with three different commercially available SiPMs.
Keywords :
DNA; biological techniques; elemental semiconductors; fluorescence; molecular biophysics; photomultipliers; photon counting; silicon; DNA-sequencing; LIF; Si; fluorescence signal; laser induced fluorescence; silicon photomultiplier; single photon counting mode; Avalanche photodiodes; Breakdown voltage; Counting circuits; Detectors; Dynamic range; Fluorescence; Photomultipliers; Signal detection; Silicon; Solid state circuits; (040.1345) Avalanche Photodiodes (APDs); (040.5570) Quantum Detectors;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9