Title :
Combining optical tweezing and confocal microscopy for the study of cell mechanics
Author :
Bomzon, Ze´ev ; Pham, Kim ; Day, Daniel ; Russell, Sarah ; Min Gu
Author_Institution :
Centre for Micro-Photonics, Swinburne Univ. of Technol., Melbourne, VIC
Abstract :
We have developed a system combining an optical tweezers and a confocal microscope for the study of cell mechanics. The system enables us to measure how mechanical forces are distributed within cells. This provides an important insight into the mechanisms by which how cells sense and respond to mechanical forces.
Keywords :
biomechanics; cellular biophysics; optical microscopy; radiation pressure; cell mechanics; confocal microscopy; optical tweezers; optical tweezing; Australia; Biomedical optical imaging; Cancer; Cells (biology); Fluorescence; Mechanical factors; Mechanical variables measurement; Optical microscopy; Optical sensors; Proteins;
Conference_Titel :
Lasers and Electro-Optics - Pacific Rim, 2007. CLEO/Pacific Rim 2007. Conference on
Conference_Location :
Seoul
Print_ISBN :
978-1-4244-1173-3
Electronic_ISBN :
978-1-4244-1174-0
DOI :
10.1109/CLEOPR.2007.4391166
