Two-photon luminescence imaging using a MEMS-based miniaturized probe

Author

Hoy, Christopher ; Durr, Nicholas ; Chen, Pengyuan ; Smith, Danielle K. ; Larson, Timothy ; Piyawattanametha, Wibool ; Ra, Hyejun ; Korgel, Brian ; Sokolov, Konstantin ; Solgaard, Olav ; Ben-Yakar, Adela

Author_Institution

Dept. of Mech. Eng., Texas Univ., Austin, TX

fYear

2008

fDate

4-9 May 2008

Firstpage

1

Lastpage

2

Abstract

We present two-photon luminescence (TPL) imaging of cancer cells through a 10 times 15 times 40 mm³ miniaturized probe employing a two-axis MEMS scanning mirror and an air-core photonic crystal fiber. The combination of TPL imaging with a small probe represents a potential method of distinguishing cancerous cells in tissue for diagnosis.

Keywords

biomedical optical imaging; cancer; cellular biophysics; fibre optic sensors; micromirrors; microsensors; photoluminescence; photonic crystals; tumours; two-photon processes; MEMS-based miniaturized probe; air-core photonic crystal fiber; cancer cells; tissue diagnosis; two-axis MEMS scanning mirror; two-photon luminescence imaging; Cancer; Laser beams; Lenses; Luminescence; Micromechanical devices; Microscopy; Mirrors; Optical imaging; Probes; Ultrafast optics; (170.2150) Endoscopic imaging; (180.4315) Nonlinear microscopy; (250.5403) Plasmonics;

fLanguage

English

Publisher

iet

Conference_Titel

Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on

Conference_Location

San Jose, CA

Print_ISBN

978-1-55752-859-9

Type

conf

Filename

4571661