Title :
Compact, rapid cell deformability measurements using diode laser bar optical trapping in microfluidics
Author :
Applegate, Robert W., Jr. ; Squier, Jeff ; Vestad, Tor ; Oakey, John ; Marr, David W M
Author_Institution :
Dept. of Phys., Colorado Sch. of Mines, Golden, CO
Abstract :
We present a simple, compact, microfluidic system that easily facilitates diode laser bar optical trapping for cell stretching measurements and particle sorting within flowing microfluidic systems for the first time.
Keywords :
biological techniques; biomechanics; cellular biophysics; measurement by laser beam; microfluidics; radiation pressure; cell stretching measurements; diode laser bar optical trapping; microfluidic system; particle sorting; rapid cell deformability measurements; Bars; Biomedical optical imaging; Charge carrier processes; Diode lasers; Fungi; Image motion analysis; Metastasis; Microfluidics; Optical microscopy; Throughput; (140.2020) Diode Lasers; (140.7010) Trapping; (170.0170) Medical optics and biotechnology; (170.0180) Microscopy; (170.1530) Cell Analysis; (170.4520) Optical Confinement and Manipulation;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9
