Title :
Diagnosis of Cervical Intraepithelial Neoplasm (CIN) Using Polarization-Sensitive Optical Coherence Tomography
Author :
Lee, Sang-Won ; Yoo, Ji-Young ; Kang, Jin-Ho ; Kang, Moon-Sik ; Jung, Soon-Hee ; Chong, YoSep ; Cha, Dong-Soo ; Han, Kyung-Hee ; Choi, Han-Young ; Kim, Beop-Min
Author_Institution :
Dept. of Biomed. Eng., Yonsei Univ., Wonju
Abstract :
We used the polarization-sensitive optical coherence tomography (PS-OCT) to measure the degrees of circular polarization (DOCP) in human cervix. It was found that DOCP measurements are sensitive to the tissue scattering changes caused by the cervical intraepithelial neoplasia. The sensitivity and specificity of the PS-OCT diagnosis were 94.4 and 90.6%.
Keywords :
biological organs; biological tissues; biomedical optical imaging; cellular biophysics; optical tomography; cervical intraepithelial neoplasm; circular polarization; human cervix; polarization-sensitive optical coherence tomography; tissue scattering; Biomedical imaging; Biomedical optical imaging; Neoplasms; Optical imaging; Optical polarization; Optical scattering; Optical sensors; Pathology; Sensitivity and specificity; Tomography;
Conference_Titel :
Lasers and Electro-Optics - Pacific Rim, 2007. CLEO/Pacific Rim 2007. Conference on
Conference_Location :
Seoul
Print_ISBN :
978-1-4244-1173-3
Electronic_ISBN :
978-1-4244-1174-0
DOI :
10.1109/CLEOPR.2007.4391525