Title : 
Contrast enhancement laser speckle imaging system using optical clearing agent
         
        
            Author : 
Son, Taeyoon ; Yoon, Jinhee ; Jung, Byungjo
         
        
            Author_Institution : 
Dept. of Biomed. Eng., Yonsei Univ., Seoul
         
        
        
        
        
        
            Abstract : 
Previous studies made efforts to enhance the contrast of laser speckle images using some kinds of mathematical and physics methods. In this paper, we suggest a new method to enhance the contrast of laser speckle images using an optical clearing agent (OCA), glycerol. The OCAs are topically applied on skin sample and speckle images were obtained at 1 hour after glycerol application. In result, we observed enhanced contrast in laser speckle images.
         
        
            Keywords : 
biomedical optical imaging; image enhancement; laser applications in medicine; organic compounds; skin; speckle; contrast enhancement; glycerol; laser speckle imaging; optical clearing agent; Adaptive optics; Biomedical imaging; Blood flow; Charge-coupled image sensors; Laser theory; Optical imaging; Optical scattering; Physics; Skin; Speckle;
         
        
        
        
            Conference_Titel : 
Lasers and Electro-Optics - Pacific Rim, 2007. CLEO/Pacific Rim 2007. Conference on
         
        
            Conference_Location : 
Seoul
         
        
            Print_ISBN : 
978-1-4244-1173-3
         
        
            Electronic_ISBN : 
978-1-4244-1174-0
         
        
        
            DOI : 
10.1109/CLEOPR.2007.4391530