Development of high performance immunoassay system using multichannel microchip

Author

Yamanaka, M. ; Sato, K. ; Tokeshi, M. ; Katou, H. ; Kimura, H. ; Kitamori, T.

Author_Institution

Sch. of Eng., Univ. of Tokyo, Japan

fYear

2001

fDate

Oct. 31 2001-Nov. 2 2001

Firstpage

26

Lastpage

27

Abstract

Immunoassay is known as one of the most important analytical methods and widely used in clinical diagnoses and biochemical studies. The conventional immunoassay, however, requires a long assay time. We developed a bead-bed immunoassay system integrated on a microchip which successfully reduces the assay time from 2 days to 30 minutes using simple operations for assay (Sato et al, 2000 and 2001). Here, aiming at high throughput assay, an integrated immunoassay system using a multichannel microchip was developed for simultaneous analyses of multiple samples.

Keywords

biosensors; microfluidics; micromachining; microsensors; microvalves; 2 day; 30 min; analytical methods; assay operations; assay throughput; assay time; biochemical studies; clinical diagnoses; immunoassay; immunoassay system; microchip integrated bead-bed immunoassay system; multichannel microchip; multichannel microchip integrated immunoassay system; simultaneous multiple sample analysis; Calibration; Chemistry; Dry etching; Fabrication; Glass; Immune system; Medical diagnostic imaging; Pressure control; Valves; Wet etching;

fLanguage

English

Publisher

ieee

Conference_Titel

Microprocesses and Nanotechnology Conference, 2001 International

Conference_Location

Shimane, Japan

Print_ISBN

4-89114-017-8

Type

conf

DOI

10.1109/IMNC.2001.984049

Filename

984049