DocumentCode
2248924
Title
Rebinding dynamics of CO to Guanidine HC1-denatured heme proteins
Author
Park, Jaeheung ; Kim, Jooyoung ; Lee, Taegon ; Lim, Manho
Author_Institution
Dept. of Chem., Pusan Nat. Univ., Busan
fYear
2007
fDate
26-31 Aug. 2007
Firstpage
1
Lastpage
2
Abstract
Rebinding dynamics of CO photolyzed from GdnHCl-denatured HbCO and MbCO in D20 at 283K was probed by femtosecond mid-IR spectroscopy. The rebinding of CO to the denatured protein is much more efficient and faster than that to the native protein, suggesting that native structure is crucial for efficient expulsion of toxic CO.
Keywords
carbon compounds; high-speed optical techniques; infrared spectra; molecular biophysics; proteins; toxicology; CO; Guanidine HCl-denatured heme proteins; femtosecond mid-IR spectroscopy; rebinding dynamics; temperature 283 K; toxic carbon monoxide expulsion; Broadband amplifiers; Optical amplifiers; Optical pulse generation; Optical pulses; Probes; Proteins; Pulse amplifiers; Semiconductor optical amplifiers; Spectroscopy; Ultrafast optics;
fLanguage
English
Publisher
ieee
Conference_Titel
Lasers and Electro-Optics - Pacific Rim, 2007. CLEO/Pacific Rim 2007. Conference on
Conference_Location
Seoul
Print_ISBN
978-1-4244-1173-3
Electronic_ISBN
978-1-4244-1174-0
Type
conf
DOI
10.1109/CLEOPR.2007.4391605
Filename
4391605
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