Two-photon-induced photoluminescence imaging of tumors using near-infrared excited gold nanoshells

Author

Park, Jaesook ; Estrada, Arnold ; Sharp, Kelly ; Sang, Krystina ; Schwartz, Jon A. ; Smith, Danielle K. ; Coleman, Chris ; Donald, P.J. ; Korgel, Brian A. ; Dunn, Andrew K. ; Tunnell, James W.

Author_Institution

Dept. of Biomed. Eng., Univ. of Texas at Austin, Austin, TX

fYear

2008

fDate

4-9 May 2008

Firstpage

1

Lastpage

2

Abstract

We report strong two-photon-induced photoluminescence (TPIP) from silica/gold nanoshells (NS). We demonstrate its potential application for imaging the 3D distribution of NS in tumors using a NIR laser scanning multi-photon microscope.

Keywords

biomedical optical imaging; cancer; gold; nanostructured materials; optical microscopy; photoluminescence; tumours; two-photon processes; Au; NIR laser scanning multiphoton microscope; background rejection; cancer imaging; hybrid metal nanoparticles; near-infrared excited gold nanoshells; signal-to-noise ratio; tumor imaging; two-photon-induced photoluminescence imaging; Biomedical optical imaging; Brightness; Gold; Laser excitation; Luminescence; Neoplasms; Optical imaging; Optical scattering; Photoluminescence; Ultrafast optics; (190.4180) Multiphoton processes; (250.5230) Photoluminescence;

fLanguage

English

Publisher

iet

Conference_Titel

Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on

Conference_Location

San Jose, CA

Print_ISBN

978-1-55752-859-9

Type

conf

Filename

4572138