Title :
The study of apoptotic morphological changes by dual-wavelength digital holographic microscopy
Author :
Khmaladze, A. ; Matz, R.S. ; Jasensky, J. ; Epstein, T. ; Zhang, C. ; Holl, M. M Banaszak ; Chen, Z.
Author_Institution :
Dept. of Chem., Univ. of Michigan, Ann Arbor, MI, USA
Abstract :
We present the study of cellular morphology changes during apoptosis by digital holographic microscopy. The population of cells undergoing staurosporine induced apoptosis was monitored in-situ for several hours and 35% overall volume decrease was observed.
Keywords :
biological techniques; cellular biophysics; holography; optical microscopy; organic compounds; apoptotic morphological changes; cellular morphology changes; dual wavelength digital holographic microscopy; staurosporine induced apoptosis; Holographic optical components; Holography; Microscopy; Optical reflection; Time measurement; Volume measurement;
Conference_Titel :
Lasers and Electro-Optics (CLEO), 2011 Conference on
Conference_Location :
Baltimore, MD
Print_ISBN :
978-1-4577-1223-4
