• DocumentCode
    2255532
  • Title

    In vivo two-photon imaging of cortical vasculature in mice to 1.5-mm depth with 1280-nm excitation

  • Author

    Kobat, Demirhan ; Horton, Nicholas G. ; Xu, Chris

  • Author_Institution
    Sch. of Appl. & Eng. Phys., Cornell Univ., Ithaca, NY, USA
  • fYear
    2011
  • fDate
    1-6 May 2011
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Deep tissue multiphoton imaging of mouse brain using 1280-nm excitation is presented. A record imaging depth of 1.5-mm in mouse cortex is achieved in vivo, approximately reaching the fundamental depth limit in scattering tissue.
  • Keywords
    bio-optics; biomedical optical imaging; blood vessels; brain; light scattering; two-photon spectroscopy; deep tissue multiphoton imaging; depth 1.5 mm; fundamental depth limit; in vivo two photon imaging; mouse brain; mouse cortex; murine cortical vasculature; scattering tissue; wavelength 1280 nm; Attenuation; Fluorescence; Imaging; In vivo; Mice; Scattering; Signal to noise ratio;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Lasers and Electro-Optics (CLEO), 2011 Conference on
  • Conference_Location
    Baltimore, MD
  • Print_ISBN
    978-1-4577-1223-4
  • Type

    conf

  • Filename
    5951254