Title :
Mid-IR pulse shaping for enhanced 2D IR spectroscopy
Author :
Shim, Sang-Hee ; Strasfeld, David B. ; Ling, Yun L. ; Zanni, Martin T.
Author_Institution :
Dept. of Chem., Univ. of Wisconsin-Madison, Madison, WI
Abstract :
The capability of 2D IR spectroscopy for elucidating time-evolving structures is enhanced by a programmable mid-IR pulse shaper that greatly improves the ease, speed and accuracy of data collection. We demonstrate our technique on a model metal carbonyl compound and then apply it to study the structural disorder of amyloid fibers composed of aggregated human islet amyloid polypeptide (hIAPP).
Keywords :
aggregation; biochemistry; biomedical measurement; infrared spectra; laser applications in medicine; molecular biophysics; molecular configurations; optical pulse shaping; organic compounds; spectrochemical analysis; 2D IR spectroscopy; amyloid fibers; human islet amyloid polypeptide aggregation; metal carbonyl compound; mid-IR pulse shaping; programmable pulse shaper; structural disorder; time-evolving structures; Biomedical optical imaging; Fiber nonlinear optics; Humans; Infrared spectra; Nonlinear optics; Optical pulse generation; Optical pulse shaping; Pulse shaping methods; Spectroscopy; Ultrafast optics; (190.0190) Nonlinear optics; (300.0300) Spectroscopy;
Conference_Titel :
Lasers and Electro-Optics, 2008 and 2008 Conference on Quantum Electronics and Laser Science. CLEO/QELS 2008. Conference on
Conference_Location :
San Jose, CA
Print_ISBN :
978-1-55752-859-9
