Diffuse coronary atheromatosis and sensitivity/specificity to detect coronary stenosis by exercise thallium-201 scintigraphy

Author

Ericsson, C.G. ; de Faire, U. ; Hamsten, A. ; Mesko, L. ; Szamosi, A. ; Zetterquist, S. ; Erhardt, L.

Author_Institution

Danderyd Hospital, Stockholm, Sweden

fYear

1988

fDate

25-28 Sep 1988

Firstpage

271

Lastpage

273

Abstract

Ninety-four men aged 30-45 years underwent planar-exercise thallium-201 scintigraphy and coronary angiography after myocardial infarction. The coronary angiograms were scored with respect to localized stenosis and diffuse atheromatosis. The patients were grouped in quartiles on the basis of the atheromatosis score. Evaluation of left-anterior-descending (LAD) coronary artery lesions showed that the sensitivity for thallium-201 scintigraphy to detect coronary stenosis with ⩾75% reduction of luminal diameter decreased from 95% in the first to 59% in the fourth quartile. Concomitantly, the specificity increased from 60% to 100%. Thus, exercise thallium-201 scintigraphy in young men after myocardial infarction is more sensitive but less specific in finding significant stenosis in the LAD coronary artery in the presence of mild, compared to a severe, artheromatosis

Keywords

cardiology; radioisotope scanning and imaging; 30 to 45 yr; ²⁰¹Tl scintigraphy; arterial lesions; coronary stenosis detection; diffuse coronary atheromatosis; localized stenosis; nuclear medicine; young men; Angiography; Arteries; Electrocardiography; Hospitals; Image segmentation; Myocardium; Physics; Physiology; Radiology; Sensitivity and specificity;

fLanguage

English

Publisher

ieee

Conference_Titel

Computers in Cardiology, 1988. Proceedings.

Conference_Location

Washington, DC

Print_ISBN

0-8186-1949-X

Type

conf

DOI

10.1109/CIC.1988.72615

Filename

72615