• DocumentCode
    2274348
  • Title

    Non-enzymatic glycation weakens trabecular bone and may influence changes in bone quality

  • Author

    Karim, Lamya ; Vashishth, Deepak

  • Author_Institution
    Rensselaer Polytech. Inst., Troy, NY, USA
  • fYear
    2010
  • fDate
    26-28 March 2010
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Non-enzymatic glycation (NEG) is associated with bone fragility. Microarchitecture and microdamage are also shown to influence bone´s mechanical properties, but it is unknown if NEG affects their alterations. Here, we show that NEG deteriorates bone´s mechanical properties and is also correlated with these two bone quality components.
  • Keywords
    biochemistry; bone; elastic moduli; enzymes; fracture mechanics; molecular biophysics; NEG; bone quality; microarchitecture; microdamage; nonenzymatic glycation; trabecular bone; Cancellous bone; Capacitive sensors; Extracellular; Humans; Measurement standards; Mechanical factors; Microarchitecture; System testing; Temperature; Tomography;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, Proceedings of the 2010 IEEE 36th Annual Northeast
  • Conference_Location
    New York, NY
  • Print_ISBN
    978-1-4244-6879-9
  • Type

    conf

  • DOI
    10.1109/NEBC.2010.5458233
  • Filename
    5458233
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=2274348