Title :
Rotational and Translational Alignment Errors in 3D Reconstruction of Virus Structures at High Resolution
Author :
Ji, Yongchang ; Marinescu, Dan C.
Author_Institution :
Sch. of Comput. Sci., Central Florida Univ., Orlando, FL
Abstract :
3D reconstruction of virus structures at high resolution using CryoTEM data requires a very accurate rotational and translational alignment of individual views obtained experimentally. We discuss the geometrical foundations and the computational problems raised by rotational and translational alignment. We also outline the basic ideas for CTF correction
Keywords :
biology computing; computational geometry; image reconstruction; image resolution; microorganisms; transmission electron microscopy; 3D reconstruction; CTF correction; CryoTEM data; rotational alignment error; translational alignment error; transmission electron microscopy; virus structure; Computer errors; Computer science; Discrete Fourier transforms; Electron beams; Electron microscopy; Genetics; Image reconstruction; Reconstruction algorithms; Spatial resolution; Viruses (medical);
Conference_Titel :
Parallel and Distributed Systems, 2005. Proceedings. 11th International Conference on
Conference_Location :
Fukuoka
Print_ISBN :
0-7695-2281-5
DOI :
10.1109/ICPADS.2005.254