• DocumentCode
    2286318
  • Title

    Control the movement of a single dsDNA by DEP

  • Author

    Chang, Chia-Jung ; Wang, Pen-Cheng ; Tseng, Fan-Gang

  • Author_Institution
    Eng. & Syst. Sci. Dept., Nat. Tsing Hua Univ., Hsinchu, Taiwan
  • fYear
    2010
  • fDate
    17-20 Aug. 2010
  • Firstpage
    1040
  • Lastpage
    1044
  • Abstract
    In this paper we demonstrate the adoption of both electrophoresis (EP) and dielectrophoretic (DEP) forces to control the movement of a single DNA and stretch this DNA as a stretched bridge across two Al metal electrodes at specific positions. The moving speed of the single DNA molecule can also be manipulated from 0.615 to 2.285μm/s inside a nano-pore region by DEP controlling the opening size of the virtual nanopore. The control of stretched DNA linear structure and moving speed will be the first step toward single DNA base pair detection in rapid nano pore DNA sequencing technology in the future.
  • Keywords
    DNA; biological techniques; electrophoresis; molecular biophysics; nanobiotechnology; DEP; DNA sequencing; base pair detection; dielectrophoretic forces; dsDNA; electrophoresis; movement control; virtual nanopore; DEP; DNA; sequencing; stretched;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Nanotechnology (IEEE-NANO), 2010 10th IEEE Conference on
  • Conference_Location
    Seoul
  • ISSN
    1944-9399
  • Print_ISBN
    978-1-4244-7033-4
  • Electronic_ISBN
    1944-9399
  • Type

    conf

  • DOI
    10.1109/NANO.2010.5697863
  • Filename
    5697863