DocumentCode
2286318
Title
Control the movement of a single dsDNA by DEP
Author
Chang, Chia-Jung ; Wang, Pen-Cheng ; Tseng, Fan-Gang
Author_Institution
Eng. & Syst. Sci. Dept., Nat. Tsing Hua Univ., Hsinchu, Taiwan
fYear
2010
fDate
17-20 Aug. 2010
Firstpage
1040
Lastpage
1044
Abstract
In this paper we demonstrate the adoption of both electrophoresis (EP) and dielectrophoretic (DEP) forces to control the movement of a single DNA and stretch this DNA as a stretched bridge across two Al metal electrodes at specific positions. The moving speed of the single DNA molecule can also be manipulated from 0.615 to 2.285μm/s inside a nano-pore region by DEP controlling the opening size of the virtual nanopore. The control of stretched DNA linear structure and moving speed will be the first step toward single DNA base pair detection in rapid nano pore DNA sequencing technology in the future.
Keywords
DNA; biological techniques; electrophoresis; molecular biophysics; nanobiotechnology; DEP; DNA sequencing; base pair detection; dielectrophoretic forces; dsDNA; electrophoresis; movement control; virtual nanopore; DEP; DNA; sequencing; stretched;
fLanguage
English
Publisher
ieee
Conference_Titel
Nanotechnology (IEEE-NANO), 2010 10th IEEE Conference on
Conference_Location
Seoul
ISSN
1944-9399
Print_ISBN
978-1-4244-7033-4
Electronic_ISBN
1944-9399
Type
conf
DOI
10.1109/NANO.2010.5697863
Filename
5697863
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