Global parametric identifiability of mechanistic models in chain polymerization

Mechanistic models of chain homopolymerization systems in isothermal batch reactors are analyzed in terms of their global parametric identifiability with respect to state-of-art measurements. The analyses include identifiability of the individual parameters (reaction rate constants) from the measurements and distinguishability of models that arise from different reaction networks. Particular systems of interest are the high-temperature batch chain homopolymerization systems. Advantages of adding spectroscopic measurements to conventional (e.g., gravimetric and chromatographic) measurements in parameter estimation studies are also discussed