Title :
Protein structure determination using 3-D grayscale skeletonization
Author :
Lee, Kevin M. ; Bhattacharya, Prabir
Author_Institution :
Dept. of Comput. Sci. & Eng., Nebraska Univ., Lincoln, NE, USA
Abstract :
This paper describes ongoing work on an algorithm for performing 3-D grayscale skeletonization. The algorithm makes use of a variation of the gray weighted distance transform without performing any prior thresholding. It is being developed as a tool for structural biologists to utilize in determining the structure of large protein molecules
Keywords :
X-ray crystallography; X-ray imaging; biological techniques; biology computing; chemistry computing; electron density; image recognition; iterative methods; proteins; transforms; 3-D grayscale skeletonization; gray weighted distance transform; large protein molecules; protein structure determination; structural biologists; Biochemistry; Biomedical optical imaging; Computer science; Crystallography; Drugs; Electrons; Gray-scale; Pattern recognition; Protein engineering; Skeleton;
Conference_Titel :
Image Analysis and Interpretation, 1998 IEEE Southwest Symposium on
Conference_Location :
Tucson, AZ
Print_ISBN :
0-7803-4876-1
DOI :
10.1109/IAI.1998.666873