Spin coated thin-film polymer waveguide Mach-Zehnder interferometer for label-free streptavidin detection

Author

Bruck, R. ; Melnik, E. ; Muellner, P. ; Hainberger, R. ; Lämmerhofer, M.

Author_Institution

Health & Environ., AIT Austrian Inst. of Technol. GmbH, Vienna, Austria

fYear

2011

fDate

18-20 May 2011

Firstpage

1

Lastpage

2

Abstract

We report the development of Mach-Zehnder interferometer biosensors based on spin coated thin-film high index contrast polymer waveguides. Despite the large wavelength of 1310 nm and the comparatively low index contrast in polymers, label-free online detection of streptavidin concentrations as low as 0.1 μg/ml (= 1.66 nMol) was achieved. The polymer-based optical sensor design is fully compatible with cost-efficient mass production technologies such as injection molding and spin coating.

Keywords

Mach-Zehnder interferometers; biochemistry; biosensors; chemical variables measurement; integrated optics; optical design techniques; optical films; optical sensors; optical waveguides; polymer films; proteins; spin coating; cost-efficient mass production technologies; injection molding; interferometer biosensors; label-free streptavidin concentration detection; polymer-based optical sensor design; spin coated thin-film polymer waveguide Mach-Zehnder interferometer; wavelength 1310 nm; Biosensors; Optical interferometry; Optical ring resonators; Optical sensors; Optical waveguides; Polymers;

fLanguage

English

Publisher

ieee

Conference_Titel

Information Photonics (IP), 2011 ICO International Conference on

Conference_Location

Ottawa, ON

Print_ISBN

978-1-61284-315-5

Type

conf

DOI

10.1109/ICO-IP.2011.5953810

Filename

5953810