• DocumentCode
    2299969
  • Title

    Infrared detection of flu viruses

  • Author

    Banerjee, Adrish ; Chakraborty, Shiladri ; Grebel, Haim

  • Author_Institution
    Electron. Imaging Center, NJIT, Newark, NJ, USA
  • fYear
    2012
  • fDate
    23-27 Sept. 2012
  • Firstpage
    153
  • Lastpage
    154
  • Abstract
    The goal of this paper is to monitor binding of viruses to a model membrane - lipid bilayer - by using Infrared (IR) spectroscopy. IR spectroscopy is a useful spectroscopic tool: it monitors bio-molecular vibrations and provides for molecular fingerprinting. It also provides information on the direction of formed hydrogen bonds when using polarized IR beams. We used graphene-coated IR mesh-screens as substrates. We demonstrated monitoring the attachment of hemagglutinin (HA) from influenza viruses to the proper receptors. Monitoring is limited to monolayer range where bonds are formed.
  • Keywords
    biomembranes; biosensors; coatings; diseases; graphene; hydrogen bonds; infrared detectors; infrared spectra; lipid bilayers; microorganisms; molecular biophysics; monolayers; proteins; vibrational states; C; biomolecular vibrations; biosensors; flu viruses; graphene-coated infrared mesh-screens; hemagglutinin attachment; hydrogen bonds; infrared detection; infrared spectroscopy; lipid bilayer; membrane; molecular fingerprinting; monolayer; polarized infrared beams; virus binding monitoring; Humans; Lipidomics; Monitoring; Proteins; Substrates; Viruses (medical);
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Photonics Conference (IPC), 2012 IEEE
  • Conference_Location
    Burlingame, CA
  • Print_ISBN
    978-1-4577-0731-5
  • Type

    conf

  • DOI
    10.1109/IPCon.2012.6358535
  • Filename
    6358535