Title :
Optical resonator-based biosensors: Plasmonic enhancements for label-free single molecule detection
Author_Institution :
Max Planck Inst. for the Sci. of Light, Erlangen, Germany
Abstract :
Microcavity biosensors derive their sensitivity from monitoring frequency shifts induced by protein binding at sites of highly confined field intensities, where field strengths can be further amplified by excitation of plasmon resonances in nanoparticle layers.
Keywords :
bioMEMS; biosensors; microcavities; microsensors; molecular biophysics; nanoparticles; optical resonators; optical sensors; plasmonics; plasmons; proteins; sensitivity; field strengths; frequency shift monitoring; label-free single molecule detection; microcavity biosensors; nanoparticle layers; optical resonator-based biosensors; plasmon resonance excitation; plasmonic enhancements; protein binding; sensitivity; Biomedical optical imaging; Biosensors; Gold; ISO standards; Optical resonators; Optical sensors; Resonant frequency;
Conference_Titel :
Photonics Conference (IPC), 2012 IEEE
Conference_Location :
Burlingame, CA
Print_ISBN :
978-1-4577-0731-5
DOI :
10.1109/IPCon.2012.6358628
