Title :
Integrated system for 3D assembly of bio-scaffolds and cells
Author :
Lang, Michael ; Wang, Wenhui ; Chen, Xiaoqi ; Woodfield, Tim
Author_Institution :
Mechatron. Dept., Univ. of Canterbury, Christchurch, New Zealand
Abstract :
Tissue engineering is a rapidly growing field with the aim of developing replacement tissues and organs for patients. An important aspect to the success of regenerated tissue is in the seeding of cells into structured porous scaffolds. This paper reports on an integrated system that is capable of printing bio-scaffold structures and automating the process of cell seeding. The two key components of the system include an in-house customized bio-scaffold printer and a spheroid seeding device. The former generates the physical bio-scaffold for cell seeding; and the latter separates and places individual cells within the porous lattice of the scaffold. Preliminary tests have shown proof of concept for the design of the system.
Keywords :
biodegradable materials; biomedical engineering; cellular biophysics; tissue engineering; 3D bioscaffold assembly; 3D cell assembly; bioscaffold printer; cell seeding; integrated system; replacement organ; replacement tissue; spheroid seeding device; tissue engineering; Fluids; Loading; Pistons; Printers; Solid modeling; Three dimensional displays;
Conference_Titel :
Automation Science and Engineering (CASE), 2010 IEEE Conference on
Conference_Location :
Toronto, ON
Print_ISBN :
978-1-4244-5447-1
DOI :
10.1109/COASE.2010.5584476
